Amitriptyline is a prescription medication used in veterinary medicine for treating behavioral disorders in small animals, including anxiety and chronic pain.
Amitriptyline is a tricyclic antidepressant that increases the amount of serotonin and norepinephrine in the brain.
Amitriptyline is generally given once or twice daily, with or without food.
Side effects of Amitriptyline can include constipation, urine holding, vomiting, diarrhea, excessive sleepiness, and decreased red and white blood cell production.
For example, serotonin syndrome can occur when given with a selective serotonin reuptake inhibitor (SSRI) like fluoxetine or a sedative like trazodone.
Overdoses of Amitriptyline can be life-threatening, with symptoms including lethargy, incoordination, vomiting, heart rhythm changes, and collapse.
Amitriptyline should be stored at controlled room temperatures between 68–77 F, in a tightly closed container to protect from moisture and light.